The APOBEC4 Polyclonal Antibody (PACO50814) is a valuable tool for researchers studying APOBEC4, a member of the APOBEC (apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like) family of proteins involved in RNA editing and immune response modulation. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.APOBEC4 is known to play a role in innate immune response and has been implicated in various disease states, including cancer and viral infections. By targeting the APOBEC4 protein, this antibody enables researchers to detect and analyze the expression of APOBEC4 in different cell types, providing insights into its function and potential therapeutic implications.
With its ability to specifically bind to APOBEC4, the PACO50814 antibody is well-suited for investigations in immunology, virology, and cancer research. Understanding the role of APOBEC4 in immune regulation and disease pathogenesis is essential for the development of novel therapies targeting this protein and its associated pathways.
APOBEC4: Putative C to U editing enzyme whose physiological substrate is not yet known. Belongs to the cytidine and deoxycytidylate deaminase family.Protein type: Hydrolase; EC 3.5.4.-Chromosomal Location of Human Ortholog: 1q25.3
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of the AID/APOBEC family of polynucleotide (deoxy)cytidine deaminases, which convert cytidine to uridine. Other AID/APOBEC family members are involved in mRNA editing, somatic hypermutation and recombination of immunoglobulin genes, and innate immunity to retroviral infection. [provided by RefSeq, Jul 2008]
