The APOBEC4 Polyclonal Antibody (PACO22531) is specifically designed for researchers studying APOBEC4, a member of the APOBEC family of proteins involved in nucleic acid editing and immune response regulation. Raised in rabbits, this antibody is highly reactive with human samples and has been validated for use in a variety of applications, including Western blotting.APOBEC4 is a crucial player in immune response regulation, with implications in diseases such as cancer and autoimmune disorders. By binding to APOBEC4 protein, this antibody enables researchers to detect and analyze its expression in different cell types, making it an excellent tool for studies in immunology and cancer research.
Understanding the role of APOBEC4 is essential for uncovering its potential as a therapeutic target in immune-related diseases. With its high specificity and sensitivity, the APOBEC4 Polyclonal Antibody (PACO22531) offers researchers a reliable tool to further explore the functions and mechanisms of APOBEC4 in health and disease.
Antibody Name:
APOBEC4 Antibody (PACO22531)
Antibody SKU:
PACO22531
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:3000
Species Reactivity:
Human
Immunogen:
Synthesized peptide derived from internal of human APOBEC4.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western blot analysis of extracts from K562 cells, using APOBEC4 antibody.
Background:
Putative C to U editing enzyme whose physiological substrate is not yet known By similarity.
APOBEC4: Putative C to U editing enzyme whose physiological substrate is not yet known. Belongs to the cytidine and deoxycytidylate deaminase family.Protein type: Hydrolase; EC 3.5.4.-Chromosomal Location of Human Ortholog: 1q25.3
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of the AID/APOBEC family of polynucleotide (deoxy)cytidine deaminases, which convert cytidine to uridine. Other AID/APOBEC family members are involved in mRNA editing, somatic hypermutation and recombination of immunoglobulin genes, and innate immunity to retroviral infection. [provided by RefSeq, Jul 2008]
