The APOBEC4 Polyclonal Antibody (PACO04250) is a valuable tool for researchers studying the APOBEC4 protein, a member of the APOBEC family of enzymes known for their role in DNA editing and immune response regulation. This antibody, produced in rabbits, demonstrates high reactivity towards human samples and is suitable for use in Western blot applications.APOBEC4 is a key player in the immune system, influencing processes such as viral restriction, antibody diversification, and tumor suppression. By targeting the APOBEC4 protein, researchers can investigate its functions and mechanisms in various cell types, providing insights into its potential implications in immunology, cancer research, and viral defense.
The precise binding of this antibody to APOBEC4 enables accurate detection and analysis, allowing for detailed exploration of the protein's functions and interactions. With its specificity and reliability, the APOBEC4 Polyclonal Antibody (PACO04250) is an essential tool for advancing our understanding of immune regulation and disease mechanisms.
Antibody Name:
APOBEC4 Antibody
Antibody SKU:
PACO04250
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
WB:1:500-1:2000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the C-terminal region of human APOBEC4.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
APOBEC4: Putative C to U editing enzyme whose physiological substrate is not yet known. Belongs to the cytidine and deoxycytidylate deaminase family.Protein type: Hydrolase; EC 3.5.4.-Chromosomal Location of Human Ortholog: 1q25.3
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of the AID/APOBEC family of polynucleotide (deoxy)cytidine deaminases, which convert cytidine to uridine. Other AID/APOBEC family members are involved in mRNA editing, somatic hypermutation and recombination of immunoglobulin genes, and innate immunity to retroviral infection. [provided by RefSeq, Jul 2008]
