The APOBEC3D Polyclonal Antibody (CAB11648) is a valuable tool for researchers studying APOBEC3D, a member of the APOBEC family of proteins involved in DNA and RNA editing processes, particularly in the context of viral restriction and cancer biology. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples, making it suitable for various applications such as Western blot and immunofluorescence.APOBEC3D has been recognized for its role in antiviral defense mechanisms, particularly against retroviruses like HIV, as well as its potential involvement in tumor development and progression.
By targeting APOBEC3D with this polyclonal antibody, researchers can detect and investigate the protein's expression and function in different cell types, shedding light on its impact on viral infections and cancer biology.With its ability to facilitate the study of APOBEC3D in various research areas, including virology, oncology, and molecular biology, the APOBEC3D Polyclonal Antibody (CAB11648) is a valuable asset for scientists seeking to unravel the complexities of APOBEC-mediated processes and develop innovative strategies for therapeutic interventions.
Product Name:
APOBEC3D Rabbit Polyclonal Antibody
SKU:
CAB11648
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 207-386 of human APOBEC3D (NP_689639.2).
This gene is a member of the cytidine deaminase gene family. It is one of a group of related genes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1 and inhibit retroviruses, such as HIV, by deaminating cytosine residues in nascent retroviral cDNA.
Purification Method:
Affinity purification
Gene ID:
140564
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using APOBEC3D Rabbit pAb (CAB11648) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
