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APOBEC3D/APOBEC3F Antibody (PACO00407)

SKU:
PACO00407
Product Type:
Antibody
Reactivity:
Human
NHP - Monkey
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
WB
IHC
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
€269
Frequently bought together:

Description

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APOBEC3D/APOBEC3F Antibody (PACO00407)

The APOBEC3D/APOBEC3F Antibody (PACO00407) is a highly specific and sensitive tool for researchers studying the APOBEC3 family of proteins, specifically APOBEC3D and APOBEC3F. This polyclonal antibody, generated in rabbits, is optimized for use in various research applications, including Western blot and immunofluorescence.APOBEC3 proteins are a family of cytidine deaminases involved in the innate immune response against viral infections and retrotransposon mobility. APOBEC3D and APOBEC3F have been shown to possess anti-viral activity against a wide range of viruses, including HIV-1 and hepatitis B virus. By targeting these specific proteins, researchers can gain valuable insights into the mechanisms of viral restriction and host defense.

The APOBEC3D/APOBEC3F Antibody (PACO00407) offers researchers a reliable tool for detecting and analyzing these important proteins in various biological samples. Its high specificity and sensitivity make it an ideal choice for studies in virology, immunology, and cancer research. By understanding the role of APOBEC3D and APOBEC3F in immune responses and viral restriction, researchers can potentially develop novel therapeutic strategies for combating viral infections and related diseases.

Antibody Name:APOBEC3D/APOBEC3F Antibody
Antibody SKU:PACO00407
Size:50ug
Host Species:Rabbit
Tested Applications:ELISA, WB, IHC
Recommended Dilutions:WB:1:500-1:2000, IHC:1:100-1:300
Species Reactivity:Human, Monkey
Immunogen:synthesized peptide derived from the Internal region of human APOBEC3D/F.
Form:Liquid
Storage Buffer:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Synonyms:APOBEC3D; Probable DNA dC->dU-editing enzyme APOBEC-3D; APOBEC3F; DNA dC->dU-editing enzyme APOBEC-3F; Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3F
UniProt Protein Function:APOBEC3D: Probable DNA cytidine deaminase involved in foreign DNA clearance. May provide cellular innate resistance to a specific panel of genetic invaders including endogenous retroelements and a subset of viruses. Belongs to the cytidine and deoxycytidylate deaminase family.
UniProt Protein Details:

Protein type:Hydrolase; EC 3.5.4.-

Chromosomal Location of Human Ortholog: 22q13.1

Cellular Component: cytoplasm

Molecular Function:zinc ion binding; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines

Biological Process: negative regulation of retroviral genome replication; innate immune response; defense response to virus

UniProt Code:Q96AK3
NCBI GenInfo Identifier:48474596
NCBI Gene ID:
NCBI Accession:Q96AK3.1
UniProt Secondary Accession:Q96AK3,Q5JZ91, Q7Z2N2, Q7Z2N5, Q7Z2N6,
Molecular Weight:46598
NCBI Full Name:DNA dC->
UniProt Protein Name:DNA dC->dU-editing enzyme APOBEC-3D
Protein Family:DNA dC->dU-editing enzyme
UniProt Gene Name:APOBEC3D  
UniProt Entry Name:ABC3D_HUMAN

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