The APOBEC3C Polyclonal Antibody (CAB14510) is a valuable tool for researchers studying APOBEC3C, a member of the APOBEC family of proteins known for their role in innate immunity and antiviral defense mechanisms. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.APOBEC3C is involved in the restriction of viral replication through cytidine deamination, leading to the inactivation of viral genomes. Understanding the function and regulation of APOBEC3C is important for investigating its potential as a target for therapeutic strategies against viral infections, including HIV.
By binding specifically to the APOBEC3C protein, this antibody enables researchers to detect and analyze its expression in various cell types, providing invaluable insights into its role in immune responses and viral defense mechanisms. Its versatility and reliability make it an essential tool for studies in virology, immunology, and infectious diseases research.
Product Name:
APOBEC3C Rabbit Polyclonal Antibody
SKU:
CAB14510
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human APOBEC3C (NP_055323.2).
This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control.
Purification Method:
Affinity purification
Gene ID:
27350
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from K-562 cells, using APOBEC3C Rabbit pAb (CAB14510) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
