The APOBEC2 Polyclonal Antibody (CAB18653) is a valuable tool for researchers studying APOBEC2, a member of the APOBEC family of proteins known for their roles in RNA and DNA editing. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to the APOBEC2 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an essential component for studies in molecular biology and genetic research.APOBEC2 is involved in diverse biological processes, including RNA editing and antiviral defense mechanisms.
Its molecular functions make it a promising target for investigating RNA modification pathways, immune response modulation, and viral infections. By understanding the mechanisms of APOBEC2, researchers can uncover new insights into gene regulation, disease development, and potential therapeutic strategies targeting RNA/DNA editing processes. Overall, the APOBEC2 Polyclonal Antibody is a powerful tool for researchers aiming to explore the functions and regulatory roles of APOBEC2 in various biological contexts, ultimately advancing our understanding of genetic processes and disease mechanisms.
Product Name:
APOBEC2 Rabbit Polyclonal Antibody
SKU:
CAB18653
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-224 of human APOBEC2 (NP_006780.1).
Enables cytidine deaminase activity and identical protein binding activity. Involved in DNA demethylation. Acts upstream of or within cytidine to uridine editing. Predicted to be active in cytoplasm and nucleus.
Purification Method:
Affinity purification
Gene ID:
10930
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using APOBEC2 Rabbit pAb (CAB18653) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.