The APOBEC1 Polyclonal Antibody (CAB16756) is a crucial tool for researchers studying APOBEC1, a protein involved in RNA editing and regulation of gene expression. This antibody, produced in rabbits, exhibits high specificity and sensitivity when used in Western blot applications with human samples.APOBEC1 is known for its role in catalyzing C-to-U editing in apolipoprotein B mRNA, leading to the production of a truncated form of the protein. Dysregulation of APOBEC1 activity has been linked to various diseases, including cancer and metabolic disorders, making it a promising target for therapeutic interventions.
By targeting the APOBEC1 protein, researchers can gain insights into its functions and regulatory mechanisms, paving the way for the development of novel treatment strategies. With its reliability and versatility, the APOBEC1 Polyclonal Antibody is an invaluable tool for studies in molecular biology, genetics, and biomedical research.
Product Name:
APOBEC1 Rabbit Polyclonal Antibody
SKU:
CAB16756
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-80 of human APOBEC1 (NP_001291495).
This gene encodes a member of the cytidine deaminase enzyme family. The encoded protein forms a multiple-protein editing holoenzyme with APOBEC1 complementation factor (ACF) and APOBEC1 stimulating protein (ASP). This holoenzyme is involved in the editing of C-to-U nucleotide bases in apolipoprotein B and neurofibromatosis-1 mRNAs. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
339
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from mouse spleen, using APOBEC1 Rabbit pAb (CAB16756) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 15s.
