The Apolipoprotein A-V Polyclonal Antibody (CAB1424) is a valuable tool for researchers studying apolipoprotein A-V, a key protein involved in lipid metabolism and regulation. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in various applications, including Western blot analysis.Apolipoprotein A-V is a crucial player in lipid metabolism, specifically in the regulation of triglyceride levels in the bloodstream.
Dysregulation of apolipoprotein A-V has been linked to various metabolic disorders, making it an interesting target for research in diseases such as dyslipidemia and cardiovascular diseases. By targeting apolipoprotein A-V with this antibody, researchers can better understand its functions and implications in lipid metabolism, potentially leading to the development of new therapeutic strategies for related disorders.
Product Name:
APOA5 Rabbit Polyclonal Antibody
SKU:
CAB1424
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 207-366 of human APOA5 (NP_443200.2).
The protein encoded by this gene is an apolipoprotein that plays an important role in regulating the plasma triglyceride levels, a major risk factor for coronary artery disease. It is a component of high density lipoprotein and is highly similar to a rat protein that is upregulated in response to liver injury. Mutations in this gene have been associated with hypertriglyceridemia and hyperlipoproteinemia type 5. This gene is located proximal to the apolipoprotein gene cluster on chromosome 11q23. Alternatively spliced transcript variants encoding the same protein have been identified.
Purification Method:
Affinity purification
Gene ID:
116519
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of Mouse liver, using APOA5 antibody (CAB1424) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 5s.
