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APOA4 Monoclonal Antibody

SKU:
CAB23893
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
$167 - $635
Frequently bought together:

Description

APOA4 Monoclonal Antibody (CAB23893)

The ApoA4 Monoclonal Antibody is a valuable tool for researchers studying apolipoprotein A4, a protein involved in lipid metabolism and cardiovascular health. This antibody, produced in mouse, is highly specific for detecting ApoA4 in human samples and is suitable for use in various laboratory techniques, including Western blot and immunohistochemistry.ApoA4 is known to play a role in the transport of lipids, including cholesterol, in the blood. It has been linked to the regulation of lipid levels and may have protective effects against atherosclerosis and cardiovascular disease.

Research into the function and regulation of ApoA4 is important for understanding its potential as a therapeutic target for metabolic disorders and cardiovascular conditions.By using the ApoA4 Monoclonal Antibody, scientists can further explore the mechanisms underlying the role of this protein in lipid metabolism and cardiovascular health. With its high specificity and reliability, this antibody is an essential tool for investigating ApoA4 in both basic research and clinical studies.

Product Name:APOA4 Monoclonal Antibody
Product Code:CAB23893
Reactivity:Human
Applications:Western blotting
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Clone No:ARC62234
Reactivity:Human
Tested Applications:WB, ELISA
Key Applications:Western blotting
Recommended Dilution:WB 1:500-1:1000
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Positive Samples:Hep G2
Cellular Location:Secreted

Apoliprotein (apo) A-IV gene contains 3 exons separated by two introns. A sequence polymorphism has been identified in the 3'UTR of the third exon. The primary translation product is a 396-residue preprotein which after proteolytic processing is secreted its primary site of synthesis, the intestine, in association with chylomicron particles. Although its precise function is not known, apo A-IV is a potent activator of lecithin-cholesterol acyltransferase in vitro.

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 21-396 of human APOA4 (NP_000473.2).
Sequence:EVSAD QVATV MWDYF SQLSN NAKEA VEHLQ KSELT QQLNA LFQDK LGEVN TYAGD LQKKL VPFAT ELHER LAKDS EKLKE EIGKE LEELR ARLLP HANEV SQKIG DNLRE LQQRL EPYAD QLRTQ VSTQA EQLRR QLTPY AQRME RVLRE NADSL QASLR PHADE LKAKI DQNVE ELKGR LTPYA DEFKV KIDQT VEELR RSLAP YAQDT QEKLN HQLEG LTFQM KKNAE ELKAR ISASA EELRQ RLAPL AEDVR GNLRG NTEGL QKSLA ELGGH LDQQV EEFRR RVEPY GENFN KALVQ QMEQL RQKLG PHAGD VEGHL SFLEK DLRDK VNSFF STFKE KESQD KTLSL PELEQ QQEQQ QEQQQ EQVQM LAPLE S
Synonyms:APOA4
Calculated MW:45kDa
Observed MW:45kDa

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