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Apoa4 Antibody (PACO24990)

SKU:
PACO24990
Product Type:
Antibody
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
€339
Frequently bought together:

Description

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Apoa4 Antibody (PACO24990)

The APOA4 Antibody (PAC024990) is a high-quality research tool designed for studying the apolipoprotein A-IV (APOA4) protein, which plays a crucial role in lipid metabolism and cholesterol homeostasis. This polyclonal antibody, generated in rabbits, offers excellent reactivity with human samples and is validated for use in various applications, including Western blotting.APOA4 is a key player in lipid absorption and metabolism, making it a promising target for research in metabolic disorders, cardiovascular diseases, and obesity. By detecting and analyzing APOA4 protein levels, researchers can gain insights into its involvement in lipid transport and metabolism, aiding in the development of potential therapeutic interventions for related conditions.

With its specificity and reliability, the APOA4 Antibody (PAC024990) is an essential tool for studies investigating the biological functions and regulatory mechanisms of APOA4 in health and disease. Whether exploring lipid metabolism pathways or evaluating APOA4 as a biomarker for disease risk, this antibody is a valuable asset for researchers in the fields of biochemistry, molecular biology, and metabolism research.

Antibody Name:Apoa4 Antibody (PACO24990)
Antibody SKU:PACO24990
Size:50ug
Host Species:Rabbit
Tested Applications:ELISA
Recommended Dilutions:
Species Reactivity:Mouse
Immunogen:Recombinant Mouse Apolipoprotein A-IV protein (21-395AA)
Form:Liquid
Storage Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method:>95%, Protein G purified
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Background:May have a role in chylomicrons and VLDL secretion and catabolism. Required for efficient activation of lipoprotein lipase by ApoC-II; potent activator of LCAT. Apoa-IV is a major component of HDL and chylomicrons.
Synonyms:Apolipoprotein A-IV (Apo-AIV) (ApoA-IV) (Apolipoprotein A4), Apoa4
UniProt Protein Function:APOA4: May have a role in chylomicrons and VLDL secretion and catabolism. Required for efficient activation of lipoprotein lipase by ApoC-II; potent activator of LCAT. Apoa-IV is a major component of HDL and chylomicrons. Synthesized primarily in the intestine and secreted in plasma. Belongs to the apolipoprotein A1/A4/E family.Protein type: Cell adhesion; Endoplasmic reticulum; Lipid-binding; Secreted; Secreted, signal peptideChromosomal Location of Human Ortholog: 9 A5.2|9 25.36 cMCellular Component: cell surface; chylomicron; extracellular matrix; extracellular region; extracellular spaceMolecular Function: antioxidant activity; cholesterol binding; cholesterol transporter activity; copper ion binding; lipid binding; phosphatidylcholine binding; protein homodimerization activityBiological Process: cholesterol biosynthetic process; cholesterol efflux; cholesterol homeostasis; cholesterol metabolic process; hydrogen peroxide catabolic process; innate immune response in mucosa; leukocyte adhesion; lipid homeostasis; lipid transport; lipoprotein metabolic process; multicellular organismal lipid catabolic process; neuron projection regeneration; phosphatidylcholine metabolic process; phospholipid efflux; positive regulation of fatty acid biosynthetic process; positive regulation of lipoprotein lipase activity; protein-lipid complex assembly; regulation of cholesterol transport; regulation of intestinal cholesterol absorption; removal of superoxide radicals; response to lipid hydroperoxide; reverse cholesterol transport; transport; triglyceride catabolic process
UniProt Protein Details:
NCBI Summary:
UniProt Code:P06728
NCBI GenInfo Identifier:110347473
NCBI Gene ID:11808
NCBI Accession:NP_031494.2
UniProt Secondary Accession:P06728,Q91XF8
UniProt Related Accession:P06728
Molecular Weight:
NCBI Full Name:apolipoprotein A-IV
NCBI Synonym Full Names:apolipoprotein A-IV
NCBI Official Symbol:Apoa4  
NCBI Official Synonym Symbols:Apoa-4  
NCBI Protein Information:apolipoprotein A-IV
UniProt Protein Name:Apolipoprotein A-IV
UniProt Synonym Protein Names:Apolipoprotein A4
Protein Family:Apolipoprotein
UniProt Gene Name:Apoa4  
UniProt Entry Name:

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