APOA1 Antibody (PACO24986)
- SKU:
- PACO24986
- Product Type:
- Antibody
- Reactivity:
- Bovine
- Rat
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
APOA1 Antibody (PACO24986)
The ApoA1 Antibody (PAC024986) is a high-quality polyclonal antibody specifically designed for research involving Apolipoprotein A1 (ApoA1), a protein associated with lipid metabolism and cardiovascular health. This antibody, raised in rabbits, exhibits high reactivity with human samples and is validated for use in various applications, including Western blot and immunohistochemistry.ApoA1 is a major component of high-density lipoprotein (HDL) particles and plays a crucial role in reverse cholesterol transport, the process by which excess cholesterol is removed from peripheral tissues and transported back to the liver for excretion.
Dysregulation of ApoA1 has been linked to a variety of cardiovascular diseases, making it a valuable target for research in cardiovascular biology and lipid metabolism.By targeting ApoA1, researchers can gain insights into the molecular mechanisms underlying lipid metabolism and cardiovascular health, as well as develop new therapeutic strategies for the treatment of cardiovascular diseases. The ApoA1 Antibody (PAC024986) is an essential tool for studying ApoA1 expression, localization, and function in various cell types and tissues, advancing our understanding of its role in health and disease.
| Antibody Name: | APOA1 Antibody (PACO24986) |
| Antibody SKU: | PACO24986 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000 |
| Species Reactivity: | Bovine, Rat, Mouse |
| Immunogen: | Recombinant Bovine Apolipoprotein A-I protein (25-265AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot Positive WB detected in: Rat liver tissue, Mouse liver tissue All lanes: APOA1 antibody at 3.4µg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 31 kDa Observed band size: 31 kDa . |
| Background: | Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility. |
| Synonyms: | Apolipoprotein A-I (Apo-AI) (ApoA-I) (Apolipoprotein A1) [Cleaved into: Proapolipoprotein A-I (ProapoA-I); Truncated apolipoprotein A-I], APOA1 |
| UniProt Protein Function: | Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility. |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | P15497 |
| NCBI GenInfo Identifier: | 75832056 |
| NCBI Gene ID: | 281631 |
| NCBI Accession: | NP_776667.2 |
| UniProt Secondary Accession: | P15497,Q3SZD9, A5D7M9 |
| UniProt Related Accession: | P15497 |
| Molecular Weight: | |
| NCBI Full Name: | apolipoprotein A-I preproprotein |
| NCBI Synonym Full Names: | |
| NCBI Official Symbol: | APOA1Â Â |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | apolipoprotein A-I |
| UniProt Protein Name: | Apolipoprotein A-I |
| UniProt Synonym Protein Names: | Apolipoprotein A1 |
| Protein Family: | Apolipoprotein |
| UniProt Gene Name: | APOA1Â Â |
| UniProt Entry Name: | APOA1_BOVIN |
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