Description
APMAP Antibody (PACO18573)
The APMAP Polyclonal Antibody (PAC018573) is a valuable tool for researchers studying APMAP, a protein involved in the regulation of cell growth and development. This antibody, raised in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the APMAP protein, this antibody enables accurate detection and analysis in a variety of cell types, making it ideal for studies in developmental biology and cancer research.
APMAP, also known as adipocyte plasma membrane-associated protein, plays a crucial role in cellular processes such as cell proliferation and differentiation. Its involvement in these processes makes it a compelling target for research into various diseases, including cancer and metabolic disorders. Understanding the function of APMAP is essential for developing therapies that target its activity and may lead to advances in the treatment of these conditions.
Antibody Name: | APMAP Antibody (PACO18573) |
Antibody SKU: | PACO18573 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:25-1:100 |
Species Reactivity: | Human |
Immunogen: | Synthetic peptide of human APMAP |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO18573(APMAP Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200). |
![]() | Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-3: Human placenta tissue, Human fetal liver tissue, 231 cells, Primary antibody: PACO18573(APMAP Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute. |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO18573(APMAP Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200). |
Background: | C20orf3, also known as APMAP (adipocyte plasma membrane-associated protein), is a 416 amino acid, single-pass type II membrane protein that belongs to the strictosidine synthase family and is thought to play a role in adipocyte differentiation. The gene encoding C20orf3 maps to human chromosome 20, which houses over 600 genes some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome. Additionally, chromosome 20 contains a region with numerous genes which are thought important for seminal production and may be potential targets for male contraception |
Synonyms: | adipocyte plasma membrane associated protein |
UniProt Protein Function: | APMAP: a single-pass type II membrane protein that may play a role in adipocyte differentiation. Belongs to the strictosidine synthase family. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Enzyme, misc. Chromosomal Location of Human Ortholog: 20p11.2 Cellular Component: cell surface; membrane; integral to membrane Molecular Function:strictosidine synthase activity; arylesterase activity Biological Process: biosynthetic process |
UniProt Code: | Q9HDC9 |
NCBI GenInfo Identifier: | 24211474 |
NCBI Gene ID: | 57136 |
NCBI Accession: | Q9HDC9.2 |
UniProt Secondary Accession: | Q9HDC9,Q6UVZ8, Q9GZS8, Q9NUB2, A8K514, B4DXG1, |
UniProt Related Accession: | Q9HDC9 |
Molecular Weight: | 32,161 Da |
NCBI Full Name: | Adipocyte plasma membrane-associated protein |
NCBI Synonym Full Names: | adipocyte plasma membrane associated protein |
NCBI Official Symbol: | APMAPÂ Â |
NCBI Official Synonym Symbols: | BSCv; C20orf3Â Â |
NCBI Protein Information: | adipocyte plasma membrane-associated protein; protein BSCv |
UniProt Protein Name: | Adipocyte plasma membrane-associated protein |
UniProt Synonym Protein Names: | Protein BSCv |
Protein Family: | Adipocyte plasma membrane-associated protein |
UniProt Gene Name: | APMAPÂ Â |
UniProt Entry Name: | APMAP_HUMAN |