APLP1 Rabbit Polyclonal Antibody (CAB6870)
- SKU:
- CAB6870
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Frequently bought together:
Description
Product Name: | APLP1 Rabbit Polyclonal Antibody |
SKU: | CAB6870 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 285-490 of human APLP1 (NP_005157.1). |
Sequence: | TPTP RPTD GVDI YFGM PGEI SEHE GFLR AKMD LEER RMRQ INEV MREW AMAD NQSK NLPK ADRQ ALNE HFQS ILQT LEEQ VSGE RQRL VETH ATRV IALI NDQR RAAL EGFL AALQ ADPP QAER VLLA LRRY LRAE QKEQ RHTL RHYQ HVAA VDPE KAQQ MRFQ VHTH LQVI EERV NQSL GLLD QNPH LAQE LRPQ IQEL LHSE HL |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | APLP; APLP1 |
Positive Sample: | Mouse brain,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cytoplasm, Single-pass type I membrane protein. |
Calculated MW: | 72kDa |
Observed MW: | 72kDa |
This gene encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described.
Purification Method: | Affinity purification |
Gene ID: | 333 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |