APLP1 Rabbit Polyclonal Antibody (CAB2634)
- SKU:
- CAB2634
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Death
Frequently bought together:
Description
Product Name: | APLP1 Rabbit Polyclonal Antibody |
SKU: | CAB2634 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 470-580 of human APLP1 (NP_005157.1). |
Sequence: | NPHL AQEL RPQI QELL HSEH LGPS ELEA PAPG GSSE DKGG LQPP DSKD DTPM TLPK GSTE QDAA SPEK EKMN PLEQ YERK VNAS VPRG FPFH SSEI QRDE LAPA GTGV SRE |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:100 - 1:500 IF/ICC,1:50 - 1:200 |
Synonyms: | APLP; APLP1 |
Positive Sample: | Mouse brain,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cytoplasm, Single-pass type I membrane protein. |
Calculated MW: | 72kDa |
Observed MW: | 100kDa |
This gene encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described.
Purification Method: | Affinity purification |
Gene ID: | 333 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |