UniProt Protein Function: | APCL: Promotes rapid degradation of CTNNB1 and may function as a tumor suppressor. May function in Wnt signaling. Belongs to the adenomatous polyposis coli (APC) family. 3 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, peripheralChromosomal Location of Human Ortholog: 19p13.3Cellular Component: actin filament; beta-catenin destruction complex; catenin complex; cytoplasm; cytoplasmic microtubule; Golgi apparatus; microtubule cytoskeleton; perinuclear region of cytoplasmMolecular Function: beta-catenin binding; gamma-catenin binding; protein bindingBiological Process: cell fate specification; cell migration; cell proliferation; negative regulation of microtubule depolymerization; pattern specification process; positive regulation of protein catabolic process; regulation of cell differentiation |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | O95996 |
NCBI GenInfo Identifier: | 74722250 |
NCBI Gene ID: | 10297 |
NCBI Accession: | O95996.1 |
UniProt Secondary Accession: | O95996,Q05BW4, Q9UBZ1, Q9UEM8, Q9UQJ8, Q9UQJ9, Q9Y632 |
UniProt Related Accession: | O95996 |
Molecular Weight: | 243,821 Da |
NCBI Full Name: | Adenomatous polyposis coli protein 2 |
NCBI Synonym Full Names: | APC2, WNT signaling pathway regulator |
NCBI Official Symbol: | APC2Â Â |
NCBI Official Synonym Symbols: | APCLÂ Â |
NCBI Protein Information: | adenomatous polyposis coli protein 2 |
UniProt Protein Name: | Adenomatous polyposis coli protein 2 |
UniProt Synonym Protein Names: | Adenomatous polyposis coli protein-like; APC-like |
Protein Family: | Acetophenone carboxylase |
UniProt Gene Name: | APC2Â Â |
UniProt Entry Name: | APC2_HUMAN |