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APC Anti-Rat CD45 Antibody [OX-1] (AGEL2446)

SKU:
AGEL2446
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Rat
Host Species:
Mouse
Isotype:
Mouse IgG1, κ
Clone:
OX-1
Conjugation:
APC
€149 - €309

Description

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APC Anti-Rat CD45 Antibody [OX-1]

The Rat Anti-CD45 Antibody (OX-1) is a vital tool for researchers studying immune cells in rats. This monoclonal antibody, produced by Assay Genie, specifically targets CD45, a common leukocyte antigen essential for T and B cell development and activation. The antibody binds with high affinity to CD45, allowing for precise detection and characterization of immune cell populations in rat samples.With its high specificity and sensitivity, the Rat Anti-CD45 Antibody (OX-1) is ideal for various immunological applications, including flow cytometry, immunofluorescence, and immunohistochemistry.

By enabling the identification and analysis of CD45-expressing cells, this antibody facilitates research in immunology, oncology, and autoimmune diseases. Researchers can use this antibody to gain insights into the role of CD45 in immune responses, inflammation, and disease progression, advancing our understanding of immune system function in rats.For researchers interested in investigating immune cell dynamics and responses in rats, the Rat Anti-CD45 Antibody (OX-1) from Assay Genie provides a reliable and effective tool for their experiments.

Product Title:APC Anti-Rat CD45 Antibody [OX-1]
SKU:AGEL2446
Size:50 Tests, 100 Tests, 200 Tests
Clone No:OX-1
Synonyms:Receptor-type tyrosine-protein phosphatase C;Leukocyte common antigen; LCA; T200; Ly-5;Ptprc;
Host Species:Mouse
Reactivity:Rat
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:APC Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:APC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P04157
Gene ID:19265
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD45 is a 180-220 kD protein also known as leukocyte common antigen (LCA). It is a protein tyrosine phosphatase with multiple isoforms differing as a result of alternative splicing of the extracellular domain and glycosylation. CD45 is expressed on all hematopoietic cells except erythrocytes and platelets; isoform expression depends on cell type, activation state, and cell maturation. CD45 functions in signal transduction through T and B cell antigen receptors. CD45 has been shown to interact with various proteins including galectin-1, CD2, CD3, and CD4. The OX-1 antibody has been shown to partially inhibit NK cell-mediated lysis of syngeneic tumor cells in vitro.

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