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APC Anti-Rat CD44H Antibody [OX-49] (AGEL2433)

SKU:
AGEL2433
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Rat
Host Species:
Mouse
Isotype:
Mouse IgG2a, κ
Clone:
OX-49
Conjugation:
APC
$215 - $551
Frequently bought together:

Description

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Product Title:APC Anti-Rat CD44H Antibody [OX-49]
SKU:AGEL2433
Size:25µg, 100µg
Clone No:OX-49
Synonyms:Pgp-1; H-CAM; CD44s;CD44H;
Host Species:Mouse
Reactivity:Rat
Application:FCM
Isotype:Mouse IgG2a, κ
Isotype Control:APC Mouse IgG2a, κ Isotype Control[C1.18.4]
Form:Liquid
Conjugation:APC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P26051
Gene ID:12505
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD44 is an 80-95 kD cell surface glycoprotein. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. It is up-regulated when T cells and B cells are activated. It was reported that CD44 is a valuable marker for memory T cells. CD44 is an adhesion molecule involved in leukocyte adhesion and homing to lymphoid organs. The OX-49 antibody reacts with CD44H (known as CD44s) expressed on most leukocytes, except for a subset of B lymphocytes. The epitope recognized by OX-49 antibody has been mapped to a region on both the standard, CD44s, and the splice variant, CD44v, isoforms of CD44. However it was reported that OX-49 antibody cannot detect the CD44V isoform, possibly due to conformational changes in the epitope.

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