The APC Anti-Rat CD3 Antibody (G4.18) is a vital tool for researchers studying immune responses in rats. This antibody, offered by Assay Genie, is specifically designed to target the CD3 protein, a key component of T cell activation and function. By binding to CD3, the antibody allows for the detection and analysis of T cells in various experimental settings.Derived from the rat, the APC Anti-Rat CD3 Antibody (G4.18) is highly specific and exhibits strong reactivity with rat samples. It is validated for use in flow cytometry applications, enabling researchers to characterize T cells and investigate their role in immune responses.
This antibody is essential for studies in immunology, transplantation research, and autoimmune disease models, as it provides valuable insights into T cell activation and regulation.By utilizing the APC Anti-Rat CD3 Antibody (G4.18) from Assay Genie, researchers can enhance their understanding of immune responses in rats and further explore the complexities of T cell biology. This antibody is a reliable tool for advancing research in fields such as immunotherapy, infectious diseases, and autoimmune disorders, ultimately contributing to the development of innovative treatment strategies and therapeutic interventions.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P19377 Q64159 D4A5M2
Gene ID:
25710,300678,315609,25300
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD3 is a complex composed of δ, γ, ε, and ζ chains. They are 20-25 kD members of the immunoglobulin superfamily and associated with the T cell receptor (TCR). CD3 is expressed on thymocytes, peripheral T cells, some NK-T cells, and dendritic epidermal T cells. CD3 is involved in antigen recognition, signal transduction, and T cell activation.