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APC Anti-Rat CD161 Antibody [3.2.3] (AGEL3429)

SKU:
AGEL3429
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Rat
Host Species:
Mouse
Isotype:
Mouse IgG1, k
Clone:
3.2.3
Conjugation:
APC
$239 - $563
Frequently bought together:

Description

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APC Anti-Rat CD161 Antibody [3.2.3]

The APC Anti-Rat CD161 Antibody (3.2.3) offered by Assay Genie is a crucial tool for researchers studying immune responses in rats. This antibody, specific to the CD161 cell surface molecule, is developed for use in flow cytometry applications, enabling the identification and analysis of CD161-expressing cells in various experimental settings.CD161, also known as NKR-P1A, is a marker associated with natural killer (NK) cells and subsets of T cells, contributing to the regulation of immune responses and surveillance against infections and tumors. The APC Anti-Rat CD161 Antibody (3.2.3) provides reliable staining of CD161 in rat samples, allowing researchers to investigate the role of CD161-expressing cells in immune function, inflammation, and disease progression.

This antibody is highly specific and optimized for flow cytometry, offering researchers a valuable tool for characterizing immune cell populations in rat models. By targeting CD161, researchers can gain insights into the functions and interactions of NK cells and T cell subsets, advancing our understanding of immune regulation and potential therapeutic strategies in cancer, infectious diseases, and autoimmune disorders.

Product Title:APC Anti-Rat CD161 Antibody [3.2.3]
SKU:AGEL3429
Size:50 Tests, 100 Tests, 200 Tests
Clone No:3.2.3
Synonyms:NKR-P1; CD161a/CD161b; NKR-P1a/KLRB1a;
Host Species:Mouse
Reactivity:Rat
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:APC Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:APC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P27471 A4KWA1 Q5NKN4 Q5NKN2
Gene ID:362443
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD161 is a 30 kD type II transmembrane C-type lectin, expressed as a homodimer. Rat NKR-P1 receptors are primarily expressed on NK cells, a subset of T cells, dendritic cells, and activated monocytes. There are three different types of NKR-P in rat, namely NKR-P1a, NKR-P1b, and NKR-P1c. NKR-P1a does not contain an ITIM structure and is an activating receptor, while NKR-P1b contains an ITIM and displays inhibitory function. LLT-1 (ligand lectin like transcript 1) is the ligand, while KLR (killer cell lectin like) functions as a receptor.

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