The APC Anti-Mouse Ly6A/E (Sca-1) Antibody (D7) from Assay Genie (www.assaygenie.com/apc-anti-mouse-ly6a-e-sca-1-antibody-d7/) is a high-quality antibody designed for research involving the Ly6A/E antigen, also known as Sca-1, in mouse samples. This antibody, raised against Ly6A/E, offers excellent reactivity and specificity, making it ideal for applications such as flow cytometry, immunohistochemistry, and immunofluorescence.Ly6A/E, or Sca-1, is a cell surface marker commonly used to identify and isolate stem and progenitor cells in mice. It is involved in various biological processes, including cell differentiation and immune responses. The APC Anti-Mouse Ly6A/E (Sca-1) Antibody (D7) enables precise detection and analysis of Ly6A/E expression in different cell types, providing researchers with valuable insights into stem cell biology, developmental processes, and immune system functions in mice.
This antibody is a valuable tool for studies in stem cell research, regenerative medicine, and immunology, where accurate identification and characterization of Ly6A/E-positive cells are crucial. With its reliable performance and specificity, the APC Anti-Mouse Ly6A/E (Sca-1) Antibody (D7) facilitates high-quality data generation and enhances the understanding of Ly6A/E biology in mouse models.
Product Title:
APC Anti-Mouse Ly6A/E (Sca-1) Antibody [D7]
SKU:
AGEL2347
Size:
50 Tests, 100 Tests, 200 Tests
Clone No:
D7
Synonyms:
Ly6a;Ly6;Ly-6A.2/Ly-6E.1;SCA-1;TAP;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2a, κ
Isotype Control:
APC Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
APC
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P05533
Gene ID:
110454
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
Ly-6A/E, also known as Sca-1, is an 18 kD member of the Ly-6 multigene family. Ly6A/E is a glycosylphosphatidylinositol (GPI)-linked protein expressed on hematopoietic stem cells. In mice expressing the Ly-6.2 haplotype (e.g., AKR, C57BL, C57BR, DBA/2, SJL, SWR, and 129), Ly-6A/E is also expressed on peripheral B lymphocytes and thymic and peripheral T lymphocytes. Strains expressing the Ly-6.1 haplotype (e.g., BALB/c, CBA, C3H/He, DBA/1, and NZB) have low Ly-6A/E expression on resting peripheral lymphocytes. The expression of Ly-6A/E on lymphocytes is upregulated upon activation from both Ly6.1 and Ly6.2 haplotype mice. Ly-6A/E is thought to be involved in the regulation of both T and B cell responses.