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APC Anti-Mouse H-2 Antibody [M1/42] (AGEL2420)

SKU:
AGEL2420
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Rat
Isotype:
Rat IgG2a, κ
Clone:
M1/42
Conjugation:
APC
€159 - €409
Frequently bought together:

Description

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APC Anti-Mouse H-2 Antibody [M1/42]

The Anti-Mouse H-2 Antibody M1/42 (AGEL2420) from Assay Genie is a valuable tool for researchers studying immune responses in mice. This monoclonal antibody specifically targets the H-2 complex, a key histocompatibility antigen important for immune recognition and response. The H-2 complex is a major histocompatibility complex (MHC) present in mice, essential for antigen presentation and immune system function. The M1/42 antibody is highly specific and validated for use in applications such as flow cytometry and immunohistochemistry, enabling precise detection and analysis of H-2 expression in diverse cell types and tissues.

By targeting the H-2 complex, researchers can gain insights into immune system regulation, antigen presentation, and immune cell interactions in mouse models. This antibody is particularly valuable for studies in immunology, transplantation research, infectious disease, and autoimmune disorders, where understanding immune responses at the molecular level is crucial for developing therapies and treatments.

Product Title:APC Anti-Mouse H-2 Antibody [M1/42]
SKU:AGEL2420
Size:25µg, 100µg
Clone No:M1/42
Synonyms:Mouse major histocompatibility complex (MHC) H-2; MHC I;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:APC Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:APC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Gene ID:111364
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:The M1/42 antibody reacts with the H-2 MHC class I alloantigens expressed on nucleated cells from mice of the a, b, d, j, k, s, and u haplotypes (Stallcup, KC et al, 1981). MHC class I is involved in antigen presentation to T cells expressing CD3/TCR and CD8 proteins.

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