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APC Anti-Mouse H-2 Antibody [M1/42] (AGEL2412)

SKU:
AGEL2412
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Rat
Isotype:
Rat IgG2a, κ
Clone:
M1/42
Conjugation:
APC
€219 - €529

Description

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APC Anti-Mouse H-2 Antibody [M1/42]

The APC anti-Mouse H-2 Antibody (M1/42) is a vital tool for researchers studying immune responses in mice. This monoclonal antibody is specifically designed to target H-2 antigens, which play a crucial role in immune recognition and response. The antibody, validated for use in flow cytometry and immunohistochemistry applications, provides high specificity and sensitivity in detecting H-2 expression on mouse cells.H-2 antigens are major histocompatibility complex (MHC) molecules that help the immune system distinguish self from non-self antigens.

By targeting these molecules, researchers can gain insights into the immune response mechanisms in mice, particularly in the context of infectious diseases, autoimmune disorders, and transplantation studies. The APC anti-Mouse H-2 Antibody (M1/42) offers reliable performance in identifying and characterizing H-2 expression levels, making it an essential tool for immunology research.

Product Title:APC Anti-Mouse H-2 Antibody [M1/42]
SKU:AGEL2412
Size:50 Tests, 100 Tests, 200 Tests
Clone No:M1/42
Synonyms:Mouse major histocompatibility complex (MHC) H-2; MHC I;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:APC Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:APC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Gene ID:111364
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:The M1/42 antibody reacts with the H-2 MHC class I alloantigens expressed on nucleated cells from mice of the a, b, d, j, k, s, and u haplotypes (Stallcup, KC et al, 1981). MHC class I is involved in antigen presentation to T cells expressing CD3/TCR and CD8 proteins.

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