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APC Anti-Mouse Fc?RI? Antibody [MAR-1] (AGEL2316)

SKU:
AGEL2316
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Armenian Hamster
Isotype:
Armenian Hamster IgG
Clone:
MAR-1
Conjugation:
APC
€139 - €289
Frequently bought together:

Description

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APC Anti-Mouse FcεRIα Antibody [MAR-1]

The APC Anti-Mouse Fc RI Antibody (MAR-1) offered by Assay Genie is a valuable tool for studying Fc receptors on mouse cells. This monoclonal antibody specifically targets the Fc receptor I (Fc RI) on mouse cells, enabling researchers to investigate the role of Fc RI in immune responses and inflammatory processes. Fc receptors play a crucial role in immune system function by regulating the binding of antibodies to immune cells. The MAR-1 antibody is highly specific and has been validated for use in flow cytometry and immunofluorescence applications, making it an essential tool for researchers studying immune cell activation, signaling pathways, and antibody-mediated immune responses in mouse models.

By using the APC Anti-Mouse Fc RI Antibody (MAR-1), researchers can gain valuable insights into the function of Fc receptors in mouse immune cells, paving the way for new discoveries in immunology, inflammation, and therapeutic development.

Product Title:APC Anti-Mouse FcεRIα Antibody [MAR-1]
SKU:AGEL2316
Size:50 Tests, 100 Tests, 200 Tests
Clone No:MAR-1
Synonyms:High affinity immunoglobulin epsilon receptor subunit alpha;Fc-epsilon RI-alpha;FcERI;Fcer1a;
Host Species:Armenian Hamster
Reactivity:Mouse
Application:FCM
Isotype:Armenian Hamster IgG
Isotype Control:APC Armenian Hamster IgG Isotype Control[PIP]
Form:Liquid
Conjugation:APC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P20489
Gene ID:14125
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:FcεRIα is a transmembrane protein belonging to the Ig superfamily. FcεRIα forms a tetrameric complex with one β and two γ-subunits. The FcεRI complex plays an important role in triggering IgE-mediated allergic reactions. It is abundantly expressed on mast and basophils and up-regulated by the presence of IgE. Following stimulation via FcεRIα, mast cells and basophils release bioactive chemical mediators such as histamine, resulting in the initiation of allergic reactions. Cross linking of the high-affinity receptor for IgE on tissue mast cells triggers immediate hypersensitivity with local symptoms. The MAR-1 monoclonal antibody reacts with the FcεRIα subunit.

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