The APC Anti-Mouse CD45.1 Antibody (A20) offered by Assay Genie is a valuable tool for research involving the CD45.1 cell surface marker in mouse models. This antibody, designed for flow cytometry applications, enables precise detection and analysis of CD45.1-expressing cells in various tissues and biological samples. With high specificity and sensitivity, researchers can confidently identify and characterize immune cell populations, monitor immune responses, and track cell migration patterns in experimental settings.CD45.1, a member of the protein tyrosine phosphatase family, is a crucial marker for distinguishing immune cell subtypes, particularly T cells, B cells, and their subsets.
Its expression patterns play a pivotal role in immunological studies, including investigating immune cell development, activation, and function in both normal and pathological conditions. By utilizing the APC Anti-Mouse CD45.1 Antibody (A20), researchers can advance their understanding of immune system dynamics and improve the accuracy of their experimental results, paving the way for insights into immune-mediated diseases, immunotherapy efficacy, and immune cell-based treatments.Order the APC Anti-Mouse CD45.1 Antibody (A20) from Assay Genie today and enhance your research capabilities in immunology, oncology, and beyond.
Product Title:
APC Anti-Mouse CD45.1 Antibody [A20]
SKU:
AGEL2311
Size:
50 Tests, 100 Tests, 200 Tests
Clone No:
A20
Synonyms:
Ly-5;L-CA;T200;CD45;Ptprc;
Host Species:
Mouse
Reactivity:
Mouse
Application:
FCM
Isotype:
Mouse IgG2a, κ
Isotype Control:
APC Mouse IgG2a, κ Isotype Control[C1.18.4]
Form:
Liquid
Conjugation:
APC
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Gene ID:
19264
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD45.1 is an alloantigen of CD45, expressed by Ly5.1 bearing mouse strains (e.g., RIII, SJL/J, STS/A, DA). CD45, a member of the protein tyrosine phosphatase (PTP) family, is a 180-240 kD glycoprotein expressed on all hematopoietic cells except mature erythrocytes and platelets. There are multiple isoforms in mice that play key roles in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation states of the cell as well as specific cell types. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.