The Anti-Mouse CD4 Antibody (RM4-5) is a valuable tool for researchers studying immune responses in mouse models. CD4 is a cell surface glycoprotein found on helper T cells, which play a crucial role in regulating the immune system. This monoclonal antibody, RM4-5, specifically targets the CD4 protein in mouse samples, enabling detection and analysis in various cell types.The RM4-5 antibody is highly specific and reactive with mouse CD4, making it ideal for use in techniques such as flow cytometry, immunohistochemistry, and immunoprecipitation. By targeting CD4, researchers can better understand T cell activation, differentiation, and function, providing insights into immune-mediated diseases, infectious agents, and therapeutic interventions.
This antibody, rigorously validated for its specificity and performance, offers reliable results and consistent data for experiments in immunology, infectious diseases, and autoimmune research. With its ability to target the critical CD4 molecule in mouse systems, the Anti-Mouse CD4 Antibody (RM4-5) is a valuable asset for scientists studying immune responses and T cell biology in preclinical models.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P06332
Gene ID:
12504
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD4 is a 55 kD protein also known as L3T4 or T4. It is a member of the Ig superfamily, primarily expressed on most thymocytes and a subset of T cells, and weakly on macrophages and dendritic cells. It acts as a co-receptor with the TCR during T cell activation and thymic differentiation by binding MHC class II and associating with the protein tyrosine kinase lck.