The Anti-Mouse CD25 Antibody (PC61.5.3) offered by AssayGenie (AGEL3246) is a valuable tool for researchers studying immune regulation and T cell biology in mice. This monoclonal antibody specifically targets CD25, a cell surface marker associated with regulatory T cells (Tregs) and activated T cells.The PC61.5.3 antibody is highly specific and sensitive, making it suitable for a variety of applications, including flow cytometry, immunohistochemistry, and Western blotting. Its ability to selectively bind to CD25 allows for precise detection and analysis of Tregs and activated T cells in mouse samples.CD25, also known as interleukin-2 receptor alpha chain, is a crucial component for the maintenance and function of Tregs, which play a key role in maintaining immune tolerance and preventing autoimmunity.
This antibody enables researchers to explore the role of CD25 in immune responses, tolerance, and inflammation, providing insights into diseases such as autoimmunity, cancer, and transplant rejection.By using the Anti-Mouse CD25 Antibody (PC61.5.3), researchers can advance their understanding of immune regulation mechanisms and potentially develop targeted therapies for immune-related disorders. Trust AssayGenie for high-quality antibodies that deliver reliable results and drive impactful research in immunology and beyond.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P01590
Gene ID:
16184
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD25 is a 55 kD glycoprotein, also known as the low affinity IL-2Rα, Ly-43, p55, or Tac. It is expressed on activated T and B cells, thymocyte subset, pre-B cells, and T regulatory cells. In association with CD122 (IL-2Rβ) and CD132(common γ chain), CD25 forms the high affinity signaling IL-2 receptor.