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APC Anti-Mouse CD163 Antibody [S15049F] (AGEL3395)

SKU:
AGEL3395
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Rat
Isotype:
Rat IgG2a, k
Clone:
S15049F
Conjugation:
APC
€209 - €499
Frequently bought together:

Description

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APC Anti-Mouse CD163 Antibody [S15049F]

The APC Anti-Mouse CD163 Antibody (S15049F) is a cutting-edge tool for researchers working with CD163, a cell surface marker associated with monocytes and macrophages in the immune system. This antibody, produced specifically for use in mouse samples, is a valuable resource for flow cytometry applications, allowing for precise and accurate identification and analysis of CD163-expressing cells in various tissues and cell types.CD163 is a key player in the immune system, primarily found on cells involved in the clearance of hemoglobin-haptoglobin complexes. Its role in regulating inflammation and scavenging processes makes it a target of interest in studies related to inflammation, infectious diseases, and tissue repair.

By utilizing the APC Anti-Mouse CD163 Antibody, researchers can delve deeper into the function and behavior of CD163-positive cells, paving the way for insights into immune responses and potential therapeutic interventions.With its specific reactivity to mouse samples and validated performance in flow cytometry, the APC Anti-Mouse CD163 Antibody is an essential tool for scientists seeking to unravel the complexities of the immune system and its interactions with various disease states. This antibody's ability to accurately detect CD163 expression in mouse models opens up new avenues for investigation in immunology, inflammation, and related fields.

Product Title:APC Anti-Mouse CD163 Antibody [S15049F]
SKU:AGEL3395
Size:50 Tests, 100 Tests, 200 Tests
Clone No:S15049F
Synonyms:M130; MM130; SCARI1;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:APC Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:APC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:Q2VLH6
Gene ID:93671
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD163 is a member of the group B scavenger receptor cysteine-rich superfamily, also known as GHI/61, M130, RM3/1, p155, hemoglobin-haptoglobin complex receptor, or macrophage-associated antigen. It is a 134 kD (non-reduced)/155 kD (reduced) glycoprotein primarily expressed on macrophages, Kupffer cells, monocytes, a subset of dendritic cells, and a subset of hematopoietic stem/progenitor cells. CD163 binds to haptoglobin-hemoglobin complex and TWEAK, and plays a role in clearing hemoglobin and regulating cytokine production by macrophages. Membrane CD163 can be cleaved by metalloproteinases (MMP), resulting in a soluble form. Elevated serum level of sCD163 has been implicated in many kinds of inflammatory diseases.

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