null

APC Anti-Mouse CD105 Antibody [MJ7/18] (AGEL2474)

SKU:
AGEL2474
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Rat
Isotype:
Rat IgG2a, κ
Clone:
MJ7/18
Conjugation:
APC
€159 - €389
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS

APC Anti-Mouse CD105 Antibody [MJ7/18]

The APC Anti-Mouse CD105 Antibody (MJ7/18) is a vital tool for researchers studying CD105, a cell surface protein known for its role in angiogenesis and vascular development. This antibody is specifically designed for use in mouse samples and is validated for flow cytometry applications. It targets the CD105 protein, allowing for precise detection and analysis in various mouse cell types, making it ideal for studies in vascular biology and cancer research.CD105, also known as endoglin, is a key regulator of endothelial cell function and is involved in processes such as cell proliferation and migration. Its role in angiogenesis has made it a promising target for research into conditions like cancer and vascular disorders.

By understanding the function of CD105, researchers can shed light on the mechanisms underlying these diseases and potentially identify new therapeutic strategies.The APC Anti-Mouse CD105 Antibody (MJ7/18) offers high specificity and sensitivity, making it a valuable tool for investigating the role of CD105 in various biological processes. Researchers in the fields of vascular biology, oncology, and regenerative medicine can benefit from the precise detection capabilities of this antibody in their experimental studies.

Product Title:APC Anti-Mouse CD105 Antibody [MJ7/18]
SKU:AGEL2474
Size:25µg, 100µg
Clone No:MJ7/18
Synonyms:Endoglin;END;Eng;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:APC Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:APC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:Q63961
Gene ID:13805
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD105 is a 90 kD homodimeric type I integral membrane glycoprotein, also known as endoglin. It is expressed on endothelial cells (especially on angiogenic endothelial cells) and upregulated by hypoxia, activated monocytes, macrophages, bone marrow stromal cells, and some cytotrophoblasts. CD105 is a receptor for TGF-β1, TGF-β3 and modulates TGF-β signaling by interacting with TGF-β receptors I and/or II. CD105 also binds other growth factors such as actvin A, BMP-2, and BMP-7. CD105 has been show to be a useful marker for identifying proliferating endothelium involved in tumor angiogenesis and can be used for tumor imaging and prognosis, and has therapeutic potential for some solid tumors and other angiogenic diseases.

Related Products