The APC Anti-Human MPO Antibody (ABT-101007) offered by AssayGenie is a highly specific monoclonal antibody designed for the detection of myeloperoxidase (MPO) in human samples. This antibody is ideal for researchers studying the role of MPO in various immune and inflammatory processes.Myeloperoxidase is a key enzyme found in neutrophils and plays a crucial role in the immune response by generating reactive oxygen species to eliminate pathogens. Abnormalities in MPO expression or activity have been linked to various diseases, including cardiovascular disorders and inflammatory conditions.The APC Anti-Human MPO Antibody (ABT-101007) is validated for use in flow cytometry and immunofluorescence applications, providing researchers with a powerful tool to investigate MPO expression and localization within different cell populations.
With its high specificity and sensitivity, this antibody enables precise detection and analysis of MPO in diverse experimental settings.Researchers in the fields of immunology, inflammation, and cardiovascular biology will find the APC Anti-Human MPO Antibody (ABT-101007) invaluable for their studies into the role of MPO in health and disease. Trust AssayGenie's high-quality antibody to deliver accurate and reliable results, driving groundbreaking discoveries in the field of medical research.
Product Name:
APC Anti-Human MPO Antibody [ABT-101007]
Product Code:
AGEL3502
Size:
20 Tests, 100 Tests, 200 Tests
Clone No:
ABT-101007
Synonyms:
Myeloperoxidase
Reactivity:
Human
Host Species:
Mouse
Applications:
ICFCM
Isotype:
Mouse IgG1, κ
Isotype Control:
APC Mouse IgG1, κ Isotype Control [MOPC-21]
Conjugation:
APC
Applications:
ICFCM
Recommended Dilution:
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Storage:
Keep as concentrated solution. Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Fluorescent Label:
APC is designed to be excited by the Red (627-640 nm) laser and detected using an optical filter centered near 660 nm (e.g., a 660/20 nm bandpass filter).
Shipping:
Biological ice pack at 4°C
Form:
Liquid
Gene ID:
4353
Swissprot:
P05164
Background Information:
Myeloperoxidase (MPO) is a heterotetrameric protein consisting of two 60 kD heavy units and two 12 kD light units. A lysosomal enzyme, MPO is able to catalyze the production of hypochlorous acid, a potent microbicidal agent, from hydrogen peroxide and chloride anion during the neutrophil respiratory burst. MPO is a major enzyme involved in the inflammatory responses of polymorphonuclear leucocytes. MPO is localized to the azurophilic granules of mature granulocytes and monocytes and is also expressed in some acute myeloid leukemia cells.