The APC Anti-Human CD81 Antibody (1.3.3.22) available at AssayGenie is a high-quality monoclonal antibody designed for research applications involving the CD81 cell surface molecule. This antibody, produced specifically for human samples, is ideal for use in flow cytometry, immunofluorescence, and immunohistochemistry experiments.CD81, a member of the tetraspanin superfamily, is involved in various cellular processes such as cell adhesion, migration, and signal transduction. It is particularly known for its role in facilitating viral entry, making it a target of interest in virology and infectious disease research. The APC Anti-Human CD81 Antibody (1.3.3.22) provides researchers with a reliable tool to study the expression and function of CD81 in different cell types and tissues.
By utilizing this antibody, researchers can elucidate the role of CD81 in diverse biological processes, including immune cell activation, intracellular signaling, and pathogen-host interactions. The specificity and sensitivity of the antibody ensure accurate and reproducible results, enabling detailed investigations into the mechanisms involving CD81 in health and disease.Overall, the APC Anti-Human CD81 Antibody (1.3.3.22) from AssayGenie is a valuable resource for scientists conducting studies in immunology, virology, cell biology, and beyond. Its robust performance and broad applicability make it a reliable tool for advancing research efforts aimed at understanding the complexities of CD81 biology and its implications in various physiological and pathological contexts.
Product Title:
APC Anti-Human CD81 Antibody [1.3.3.22]
SKU:
AGEL2838
Size:
20 Tests, 100 Tests, 200 Tests
Clone No:
1.3.3.22
Synonyms:
CD81 antigen;CD81;26 kDa cell surface protein TAPA-1;Target of the antiproliferative antibody 1.Tetraspanin-28;Tspan-28;APA1; TSPAN28;
Host Species:
Mouse
Reactivity:
Human
Application:
FCM
Isotype:
Mouse IgG1, κ
Isotype Control:
APC Mouse IgG1, κ Isotype Control[MOPC-21]
Form:
Liquid
Conjugation:
APC
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P60033
Gene ID:
975
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD81 is a 26 kD non-glycosylated member of the tetraspanin superfamily (TM4SF), also known as TAPA-1 (target of an antiproliferative antibody). CD81 is expressed on T and B cells, NK cells, monocytes, dendritic cells, thymocytes, endothelial cells, and fibroblasts. It also has low levels of expression on granulocytes. CD81 induces B cell adhesion via VLA-4 integrin and has been shown to play a role in early T cell development. CD81 associates with several other cell-surface proteins in a multimolecular complex, including CD19, CD21, CD20, CD37, CD53, and CD82 in B cells, and CD4, CD8 and CD82 in T cells.