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APC Anti-Human CD80 Antibody [2D10] (AGEL2470)

SKU:
AGEL2470
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Human
Host Species:
Mouse
Isotype:
Mouse IgG1, κ
Clone:
2D10
Conjugation:
APC
€169 - €579
Frequently bought together:

Description

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APC Anti-Human CD80 Antibody [2D10]

The Anti-Human CD80 Antibody (2D10) offered by Assay Genie is a vital tool for researchers studying immune responses and cell signaling pathways. This monoclonal antibody specifically targets CD80, a crucial costimulatory molecule involved in T cell activation and regulation of immune responses.CD80, also known as B7-1, plays a pivotal role in antigen presentation and T cell activation, making it a key player in the adaptive immune system. The CD80 Antibody (2D10) is highly specific to human samples and has been rigorously validated for use in various applications, including flow cytometry, immunohistochemistry, and ELISA.

By targeting CD80 with precision, researchers can investigate its involvement in diseases such as autoimmune disorders, infectious diseases, and transplant rejection. Understanding the regulation of CD80 expression and function can provide insight into therapeutic strategies aimed at modulating immune responses and treating immune-related disorders.Enhance your research capabilities with the Anti-Human CD80 Antibody (2D10) from Assay Genie, a reliable tool for unraveling the complexities of immune regulation and T cell activation.

Product Title:APC Anti-Human CD80 Antibody [2D10]
SKU:AGEL2470
Size:20 Tests, 100 Tests, 200 Tests
Clone No:2D10
Synonyms:T-lymphocyte activation antigen CD80;B7-1; B7; BB1;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:APC Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:APC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P33681
Gene ID:941
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD80 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD80 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD80 appears to be expressed later in the immune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

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