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APC Anti-Human CD62L Antibody [HI62L] (AGEL3486)

SKU:
AGEL3486
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Human
Host Species:
Mouse
Isotype:
Mouse IgG2a, k
Clone:
HI62L
Conjugation:
APC
€199 - €709
Frequently bought together:

Description

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APC Anti-Human CD62L Antibody [HI62L]

The APC Anti-Human CD62L Antibody (HI62L) offered by Assay Genie is a high-quality reagent designed for the detection and analysis of CD62L, a key adhesion molecule involved in immune cell migration and activation. This antibody, optimized for use in flow cytometry applications, exhibits strong reactivity with human samples, allowing for precise identification and quantification of CD62L-expressing cells.CD62L, also known as L-selectin, plays a crucial role in mediating the recruitment of immune cells to sites of inflammation and injury. Understanding the expression and function of CD62L is essential for unraveling the mechanisms underlying immune responses and inflammatory processes.

The APC Anti-Human CD62L Antibody (HI62L) can aid researchers in investigating the roles of CD62L in various physiological and pathological conditions, including immune disorders, infectious diseases, and autoimmune disorders.With its high specificity and sensitivity, this antibody is a valuable tool for studies in immunology, cell biology, and clinical research. Whether exploring immune cell trafficking, characterizing immune cell subsets, or elucidating the role of CD62L in disease pathogenesis, the APC Anti-Human CD62L Antibody (HI62L) provides reliable and reproducible results to advance scientific understanding in the field.

Product Title:APC Anti-Human CD62L Antibody [HI62L]
SKU:AGEL3486
Size:20 Tests, 100 Tests, 200 Tests
Clone No:HI62L
Synonyms:L-selectin;Sell;CD62 antigen-like family member L;LAM-1;LECAM1;Lymph node homing receptor;Ly-22; CD62L;Lnhr;Ly22;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG2a, κ
Isotype Control:APC Mouse IgG2a, κ Isotype Control[C1.18.4]
Form:Liquid
Conjugation:APC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P14151
Gene ID:6402
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD62L is a 74-95 kD single chain type I glycoprotein referred to as L-selectin or LECAM-1. It is expressed on most peripheral blood B cells, subsets of T and NK cells, monocytes, granulocytes, and certain hematopoietic malignant cells. CD62L binds to carbohydrates present on certain glycoforms of CD34, glycam-1, and MAdCAM-1 and with a low affinity to anionic oligosaccharide sequences related to sialylated Lewis X (sLex, CD15s) through its C-type lectin domain. CD62L is important for the homing of naïve lymphocytes to high endothelial venules in peripheral lymph nodes and Peyer's patches. It also plays a role in leukocyte rolling on activated endothelial cells.

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