The APC Anti-Human CD56 Antibody (5.1H11) from Assay Genie is a highly specific monoclonal antibody designed for the detection and analysis of CD56, a cell surface marker also known as neural cell adhesion molecule (NCAM). This antibody is optimized for use in flow cytometry and immunohistochemistry applications, making it an essential tool for studying CD56 expression in various human samples.CD56 is a key molecule involved in cell adhesion, migration, and signal transduction, playing important roles in neural development, immune responses, and tumor progression. By targeting CD56 with this antibody, researchers can investigate its expression patterns in different cell populations and tissues, providing valuable insights into its involvement in various physiological and pathological processes.
The APC Anti-Human CD56 Antibody (5.1H11) is rigorously validated to ensure high specificity and sensitivity, making it a reliable choice for studies in immunology, oncology, and neuroscience. With its ability to accurately detect CD56 expression, this antibody opens up new avenues for research aimed at understanding the functions of CD56 and its implications in health and disease.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P13591
Gene ID:
4684
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD56 is a single transmembrane glycoprotein also known as NCAM (Neural Cell Adhesion Molecule), Leu-19, or NKH1. It is a member of the Ig superfamily. The 140 kD isoform is expressed on NK cells and NK-T cells. CD56 is also expressed in the brain (cerebellum and cortex) and at neuromuscular junctions. Certain large granular lymphocyte (LGL) leukemias, small-cell lung carcinomas, neuronal derived tumors, myelomas, and myeloid leukemias also express CD56. CD56 plays a role in homophilic and heterophilic adhesion via binding to itself or heparin sulfate.