The APC Anti-Human CD44 Antibody (P2A1) offered by AssayGenie is an essential tool for researchers studying CD44, a key cell surface protein involved in cell adhesion and migration processes. This antibody is specifically designed for use in flow cytometry applications, allowing for the precise detection and analysis of CD44 expression on human cells.CD44 is a multifunctional molecule that plays crucial roles in various physiological and pathological processes, including cell adhesion, migration, and signaling. Its expression levels have been linked to cancer progression, stem cell function, and immune responses.
By targeting CD44 with the APC Anti-Human CD44 Antibody (P2A1), researchers can gain valuable insights into the role of this protein in different cellular contexts.With high specificity and sensitivity, this antibody enables accurate identification and quantification of CD44-expressing cells, making it a valuable tool for studies in immunology, oncology, and stem cell biology. Researchers can rely on the APC Anti-Human CD44 Antibody (P2A1) from AssayGenie to facilitate their investigations into the functions and mechanisms of CD44 in various biological processes.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P16070
Gene ID:
960
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD44 is a 80-95 kD glycoprotein also known as Hermes, Pgp1, H-CAM, or HUTCH. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. As B and T cells become activated or progress to the memory stage, CD44 expression increases from a low or mid level of intensity to high expression levels. Thus, CD44 has been reported to be a valuable marker for memory cell subsets. CD44 is an adhesion molecule involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to the sites of inflammation, and leukocyte aggregation.