The APC Anti-Human CD4 Antibody (SK3) is a vital tool for researchers studying CD4, a key cell surface marker involved in immune function and T cell activity. This antibody, derived from the SK3 hybridoma, offers high specificity and sensitivity for human CD4 detection in flow cytometry and immunofluorescence applications.CD4 is a glycoprotein found on the surface of T helper cells, crucial for coordinating immune responses and regulating functions of other immune cells. The APC Anti-Human CD4 Antibody (SK3) recognizes the CD4 antigen with precision, enabling accurate identification and analysis of CD4-expressing cells in diverse biological samples.
This antibody's reliability and reproducibility make it an excellent choice for immunology studies, infectious disease research, and clinical diagnostics related to immune cell profiling. By targeting CD4, researchers can gain insights into immune system dynamics, immune cell interactions, and disease mechanisms, paving the way for innovative therapeutic strategies and diagnostic approaches in various fields of biomedicine.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P01730
Gene ID:
920
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD4, also known as T4, is a 55 kD single-chain type I transmembrane glycoprotein expressed on most thymocytes, a subset of T cells, and monocytes/macrophages. CD4, a member of the Ig superfamily, recognizes antigens associated with MHC class II molecules and participates in cell-cell interactions, thymic differentiation, and signal transduction. CD4 acts as a primary receptor for HIV, binding to HIV gp120. CD4 has also been shown to interact with IL-16.