The APC Anti-Human CD39 Antibody (A1) offered by AssayGenie is a cutting-edge tool for researchers delving into immune regulation and inflammation. This antibody specifically targets CD39, a cell surface molecule known for its role in immune responses and inflammation modulation. Derived from high-quality sources, this antibody is expertly designed for use in various immunological studies, particularly in cancer research and autoimmune disorders. It binds effectively to the CD39 protein, enabling precise detection and analysis in a range of cell types. Validated for Western blot applications, this antibody provides reliable results and enhances the understanding of CD39 function in immune response modulation.
CD39 is a key player in immune homeostasis, influencing inflammatory processes and allergic reactions. By targeting this molecule, researchers gain valuable insights into the mechanisms governing immune function and its implications in diseases such as cancer and chronic inflammatory conditions. The APC Anti-Human CD39 Antibody (A1) is an essential tool for unraveling the complexities of immune regulation and developing novel therapeutic strategies.
Product Title:
APC Anti-Human CD39 Antibody [A1]
SKU:
AGEL2290
Size:
20 Tests, 100 Tests, 200 Tests
Clone No:
A1
Synonyms:
SPG64;NTPDase1;ATPDase;CD 39;
Host Species:
Mouse
Reactivity:
Human
Application:
FCM
Isotype:
Mouse IgG1, κ
Isotype Control:
APC Mouse IgG1, κ Isotype Control[MOPC-21]
Form:
Liquid
Conjugation:
APC
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P49961
Gene ID:
953
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
Human CD39 is an integral membrane protein with two transmembrane domains. It exists as a homotetramer. Expression of CD39 is found on activated lymphocytes, a subset of T cells and B cells, and dendritic cells with weak staining on monocytes and granulocytes. CD39 and CD73 have been found on regulatory T cells, specifically the effector/memory like T cells. CD39 can hydrolyze both nucleoside triphosphates and diphosphates. CD39 is the dominant ecto nucleotidase of vascular and placental trophoblastic tissues and appears to modulate the functional expression of type 2 purinergic (P2) G protein coupled receptors (GPCRs). CD39 has intrinsic ecto-ATPase activity. Expression of CD39 is induced on T cells and increased on B cells as a late activation antigen. Product Details