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APC Anti-Human CD22 Antibody [HIB22] (AGEL3438)

SKU:
AGEL3438
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Human
Host Species:
Mouse
Isotype:
Mouse IgG1, k
Clone:
HIB22
Conjugation:
APC
€179 - €709
Frequently bought together:

Description

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APC Anti-Human CD22 Antibody [HIB22]

The APC Anti-Human CD22 Antibody (HIB22) offered by AssayGenie is a powerful tool for research in immunology and hematological malignancies. CD22 is a B-cell specific transmembrane glycoprotein involved in regulating B-cell activation and survival, making it a key target for therapeutic interventions in B-cell related diseases.This antibody, optimized for use in flow cytometry and immunohistochemistry applications, specifically detects the CD22 protein in human samples with high sensitivity and specificity.

By targeting CD22, researchers can analyze B-cell populations, investigate signaling pathways, and explore potential therapeutic targets for diseases such as B-cell lymphomas and leukemias.With its reliable performance and validated results, the APC Anti-Human CD22 Antibody (HIB22) from AssayGenie is an essential tool for advancing research in B-cell biology and clinical studies related to B-cell disorders.

Product Title:APC Anti-Human CD22 Antibody [HIB22]
SKU:AGEL3438
Size:20 Tests, 100 Tests, 200 Tests
Clone No:HIB22
Synonyms:B-cell receptor CD22;Cd22;B-lymphocyte cell adhesion molecule;BL-CAM;Sialic acid-binding Ig-like lectin 2;Siglec-2;T-cell surface antigen Leu-14;CD22;Lyb-8; Siglec2;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:APC Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:APC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P20273
Gene ID:933
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD22 is a 130 kD type I transmembrane glycoprotein also known as Siglec-2 and BL-CAM. It is a member of the immunoglobulin superfamily (sialoadhesion subgroup). CD22 is expressed in the cytoplasm of pro-B and pre-B cells, and on the surface of mature B and activated B cells, but not on plasma cells. CD22 is present in the B cell receptor complex and associates with SHP-1, Syk, Lck, Lyn, and phospholipase Cγ1. A primary function of CD22 is thought to be in limiting antigen receptor signaling by modulating B cell activation threshold. CD22 has been shown to bind to CD45RO and CD75, although the natural ligands for this molecule remain controversial.

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