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APC Anti-Human CD193/CCR3 Antibody [5E8] (AGEL3404)

SKU:
AGEL3404
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Human
Host Species:
Mouse
Isotype:
Mouse IgG2b, k
Clone:
[5E8]
Conjugation:
APC
€229 - €809
Frequently bought together:

Description

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APC Anti-Human CD193/CCR3 Antibody [5E8]

The APC Anti-Human CD193 (CCR3) Antibody (5E8) offered by AssayGenie is a cutting-edge tool for researchers studying human CCR3, a cell surface receptor involved in immune responses and inflammation. This antibody, developed using advanced technology, delivers exceptional specificity and sensitivity for detecting and analyzing CD193 (CCR3) in various experimental settings.CCR3 is a crucial receptor associated with allergic responses, inflammatory processes, and immune cell recruitment. By targeting this receptor with the APC Anti-Human CD193 Antibody (5E8), researchers gain valuable insights into the mechanisms underlying these immune pathways. This antibody has been rigorously validated for flow cytometry applications, ensuring reliable and reproducible results in studies focusing on immune cell populations and inflammatory conditions.

With its high reactivity and specificity towards human CD193 (CCR3), this antibody is an indispensable tool for investigators exploring the role of CCR3 in diseases such as asthma, allergic disorders, and certain types of cancers. By elucidating the functions of CCR3 using this advanced antibody, researchers can pave the way for the development of novel therapeutic strategies targeting immune-related conditions.In summary, the APC Anti-Human CD193 (CCR3) Antibody (5E8) from AssayGenie is a premium reagent that empowers researchers to delve deeper into the complex interplay of immune responses mediated by CCR3, opening new avenues for innovative discoveries in immunology and disease research.

Product Title:APC Anti-Human CD193/CCR3 Antibody [5E8]
SKU:AGEL3404
Size:20 Tests, 100 Tests, 200 Tests
Clone No:5E8
Synonyms:CC CKR3; MIP1-alpha receptor like-2; eotaxin receptor;CCR;C-C chemokine receptor type 3;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG2b, κ
Isotype Control:APC Mouse IgG2b, κ Isotype Control[MPC-11]
Form:Liquid
Conjugation:APC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P51677
Gene ID:1232
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD193, also known as CC-chemokine receptor 3 (CCR3), CC CKR3, MIP1-alpha receptor like-2, and eotaxin receptor, is a member of the G protein-coupled seven transmembrane receptors family. It binds to the CC chemokines eotaxin, eotaxin-2, and eotaxin-3 with high affinity. CCR3 has also been reported to bind RANTES, MCP-3, and MCP-4 with low affinity. CCR3 receptor is expressed on human eosinophils, basophils, mast cells, mononuclear phagocytes, platelets, CD34+ hematopoietic progenitor cells, Th2-like lymphocytes, and keratinocytes. CCR3 is thought to play a role in allergic diseases such as bronchial asthma and allergic rhinitis. CCR3 is a co-receptor for HIV-1 and HIV-2, and the binding of eotaxin with CCR3 has been shown to inhibit HIV infection in some cell types.

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