The APC Anti-Human CD19 Antibody (CB19) available at www.assaygenie.com/apc-anti-human-cd19-antibody-cb19/ is a cutting-edge tool for researchers focused on studying CD19, a key protein found on the surface of B cells. This monoclonal antibody is optimized for human samples and is specifically designed for flow cytometry applications. By targeting the CD19 protein, this antibody allows for precise detection and analysis of B cells in various research contexts, making it an essential reagent for immunology, oncology, and autoimmune disease studies.
CD19 is a crucial marker for B cell development and function, playing a vital role in B cell activation, differentiation, and signaling. Dysregulation of CD19 expression is implicated in various immunological disorders, including B cell malignancies and autoimmune diseases. Understanding the role of CD19 in these conditions is essential for the development of targeted therapies and diagnostics. This antibody opens up new possibilities for exploring the biology of CD19-expressing cells and their role in health and disease.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P15391
Gene ID:
930
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD19 is a 95 kD type I transmembrane glycoprotein also known as B4. It is a member of the immunoglobulin superfamily expressed on B-cells (from pro-B to blastoid B cells, absent on plasma cells) and follicular dendritic cells. CD19 is involved in B cell development, activation, and differentiation. CD19 forms a complex with CD21 (CR2) and CD81 (TAPA-1), and functions as a BCR co-receptor.