The APBA3 Polyclonal Antibody (PACO05775) from AssayGenie is a versatile tool for researchers studying the APBA3 protein, which is involved in various cellular processes such as cell signaling and synaptic transmission. This high-quality antibody, produced in rabbits, is specifically designed for use in Western blot applications and is highly reactive with human samples.APBA3, also known as amyloid beta protein-binding family A member 3, plays a key role in neuronal function and has been implicated in neurological disorders such as Alzheimer's disease.
By targeting the APBA3 protein, researchers can gain valuable insights into its function and potential therapeutic targets for neurodegenerative diseases.With its ability to detect and analyze APBA3 in different cell types, this antibody is an essential tool for studies in neuroscience and neurology, providing researchers with the means to further understand the mechanisms underlying neuronal communication and potential treatment options for neurological disorders.
Antibody Name:
APBA3 Antibody (PACO05775)
Antibody SKU:
PACO05775
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IHC
Recommended Dilutions:
ELISA:1:40000, WB:1:500-1:2000, IHC:1:100-1:300
Species Reactivity:
Human
Immunogen:
Synthesized peptide derived from the Internal region of human X11 γ .
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
APBA3; MINT3; X11L2; Amyloid β A4 precursor protein-binding family A member 3; Adapter protein X11γ; Neuron-specific X11L2 protein; Neuronal Munc18-1-interacting protein 3; Mint-3
UniProt Protein Function:
APBA3: May modulate processing of the beta-amyloid precursor protein (APP) and hence formation of beta-APP. May enhance the activity of HIF1A in macrophages by inhibiting the activity of HIF1AN.Protein type: Motility/polarity/chemotaxisChromosomal Location of Human Ortholog: 19p13.3Cellular Component: perinuclear region of cytoplasmMolecular Function: enzyme binding; enzyme inhibitor activity; protein bindingBiological Process: negative regulation of catalytic activity
UniProt Protein Details:
NCBI Summary:
The protein encoded by this gene is a member of the X11 protein family. It is an adapter protein that interacts with the Alzheimer's disease amyloid precursor protein. This gene product is believed to be involved in signal transduction processes. This gene is a candidate gene for Alzheimer's disease. [provided by RefSeq, Jul 2008]
