APBA1 Rabbit Polyclonal Antibody (CAB18582)
- SKU:
- CAB18582
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | APBA1 Rabbit Polyclonal Antibody |
SKU: | CAB18582 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 240-390 of human APBA1 (NP_001154.2). |
Sequence: | ERSD GESD SPEK EAEF APYP RMDS YEQE EDID QIVA EVKQ SMSS QSLD KAAE DMPE AEQD LERP PTPA GGRP DSPG LQAP AGQQ RAVG PAGG GEAG QRYS KEKR DAIS LAIK DIKE AIEE VKTR TIRS PYTP DEPK EPIW VMRQ DISP TRD |
Tested Applications: | IHC-P IF/ICC ELISA |
Recommended Dilution: | IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | X11; X11A; LIN10; MINT1; D9S411E; X11ALPHA; APBA1 |
Cellular Localization: | cytoplasm, cytosol, dendritic spine, glutamatergic synapse, Golgi apparatus, nucleus, perinuclear region of cytoplasm, plasma membrane, presynaptic active zone membrane, Schaffer collateral - CA1 synapse, synaptic vesicle |
Calculated MW: | 93kDa |
Observed MW: | Refer to figures |
The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion.
Purification Method: | Affinity purification |
Gene ID: | 320 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |