The AP3S2 Polyclonal Antibody (CAB17607) is a valuable tool for researchers studying AP3S2, a subunit of the AP-3 adaptor complex involved in protein sorting and trafficking within cells. This rabbit-derived antibody is highly specific to human samples and has been validated for use in Western blot applications. By binding to the AP3S2 protein, this antibody enables precise detection and analysis in various cell types, making it an essential component for investigations in cell biology and molecular biology research.AP3S2 plays a crucial role in vesicular trafficking processes, ensuring the proper delivery of cargo molecules to their designated destinations within the cell.
Dysregulation of AP3S2 function has been implicated in various human diseases, including neurodegenerative disorders and metabolic syndromes. By studying the function and regulation of AP3S2 with this antibody, researchers can gain insights into the underlying mechanisms of these conditions and potentially identify novel therapeutic targets for future interventions.
Product Name:
AP3S2 Rabbit Polyclonal Antibody
SKU:
CAB17607
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-193 of human AP3S2 (NP_005820.1).
axon cytoplasm, early endosome, Golgi apparatus, presynapse
Calculated MW:
22kDa
Observed MW:
22kDa
Predicted to be involved in anterograde synaptic vesicle transport and vesicle-mediated transport. Located in intracellular membrane-bounded organelle. Part of AP-3 adaptor complex.
Purification Method:
Affinity purification
Gene ID:
10239
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using AP3S2 Rabbit pAb (CAB17607) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
