AP3D1 Rabbit Polyclonal Antibody (CAB13058)
- SKU:
- CAB13058
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | AP3D1 Rabbit Polyclonal Antibody |
SKU: | CAB13058 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 520-700 of human AP3D1 (NP_003929.4). |
Sequence: | AVYV QNVV KLYA SILQ QKEQ AGEA EGAQ AVTQ LMVD RLPQ FVQS ADLE VQER ASCI LQLV KHIQ KLQA KDVP VAEE VSAL FAGE LNPV APKA QKKV PVPE GLDL DAWI NEPL SDSE SEDE RPRA VFHE EEQR RPKH RPSE ADEE ELAR RREA RKQE QANN PFYI KSSP SPQK RYQD TPGV E |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | ADTD; HPS10; hBLVR; AP3D1 |
Positive Sample: | LO2,U-87MG,Mouse kidney,Mouse brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Cytoplasmic side, Golgi apparatus membrane, Peripheral membrane protein. |
Calculated MW: | 130kDa |
Observed MW: | 110kDa |
The protein encoded by this gene is a subunit of the AP3 adaptor-like complex, which is not clathrin-associated, but is associated with the golgi region, as well as more peripheral structures. The AP-3 complex facilitates the budding of vesicles from the golgi membrane, and may be directly involved in trafficking to lysosomes. This subunit is implicated in intracellular biogenesis and trafficking of pigment granules, and possibly platelet dense granules and neurotransmitter vesicles. Defects in this gene are a cause of a new type of Hermansky-Pudlak syndrome.
Purification Method: | Affinity purification |
Gene ID: | 8943 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |