The AP3B1 Polyclonal Antibody (CAB7019) is a valuable tool for researchers studying AP3B1, a key protein involved in intracellular protein trafficking. This antibody, developed through immunization of rabbits, demonstrates high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to the AP3B1 protein, researchers can accurately detect and analyze its expression in a variety of cell types.AP3B1 plays a crucial role in sorting proteins to their correct destinations within the cell, making it essential for proper cellular function. Dysregulation of AP3B1 has been linked to various diseases, including Hermansky-Pudlak syndrome and some types of cancer.
Thus, studying the function of AP3B1 using the CAB7019 antibody may provide insights into disease mechanisms and potential therapeutic targets.With its reliability and specificity, the AP3B1 Polyclonal Antibody is a valuable asset for researchers working in cell biology, molecular biology, and diseases related to protein trafficking. Its ability to pinpoint AP3B1 expression in cells offers a powerful tool for advancing our understanding of cellular processes and disease pathology.
Product Name:
AP3B1 Rabbit Polyclonal Antibody
SKU:
CAB7019
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 895-1094 of human AP3B1 (NP_003655.3).
This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. The encoded protein is part of the heterotetrameric AP-3 protein complex which interacts with the scaffolding protein clathrin. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 2. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
8546
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using AP3B1 Rabbit pAb (CAB7019) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
