AP3B1 Rabbit Polyclonal Antibody (CAB7019)
- SKU:
- CAB7019
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | AP3B1 Rabbit Polyclonal Antibody |
SKU: | CAB7019 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 895-1094 of human AP3B1 (NP_003655.3). |
Sequence: | FGDK MVSI QITL NNTT DRKI ENIH IGEK KLPI GMKM HVFN PIDS LEPE GSIT VSMG IDFC DSTQ TASF QLCT KDDC FNVN IQPP VGEL LLPV AMSE KDFK KEQG VLTG MNET SAVI IAAP QNFT PSVI FQKV VNVA NVGA VPSG QDNI HRFA AKTV HSGS LMLV TVEL KEGS TAQL IINT EKTV IGSV LLRE LKPV LSQG |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | PE; HPS; HPS2; ADTB3; ADTB3A; AP3B1 |
Positive Sample: | SKOV3,SW620,Mouse liver |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasmic side, Cytoplasmic vesicle, Golgi apparatus, Peripheral membrane protein, clathrin-coated vesicle membrane. |
Calculated MW: | 121kDa |
Observed MW: | 132kDa |
This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. The encoded protein is part of the heterotetrameric AP-3 protein complex which interacts with the scaffolding protein clathrin. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 2. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 8546 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |