AP2M1 Rabbit Monoclonal Antibody (CAB11070)
- SKU:
- CAB11070
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | AP2M1 Rabbit Monoclonal Antibody |
SKU: | CAB11070 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 300-400 of human AP2M1 (Q96CW1). |
Sequence: | KLEV KVVI KSNF KPSL LAQK IEVR IPTP LNTS GVQV ICMK GKAK YKAS ENAI VWKI KRMA GMKE SQIS AEIE LLPT NDKK KWAR PPIS MNFE VPFA PSGL K |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | mu2; AP50; MRD60; CLAPM1; AP2M1 |
Positive Sample: | 293T,HepG2,U-87MG,Mouse lung,Mouse liver,Mouse brain,Mouse spleen,Rat brain,Rat spleen |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cytoplasmic side, Membrane, Peripheral membrane protein, coated pit. |
Calculated MW: | 50kDa |
Observed MW: | 50kDa |
This gene encodes a subunit of the heterotetrameric coat assembly protein complex 2 (AP2), which belongs to the adaptor complexes medium subunits family. The encoded protein is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes. The encoded protein may also play an important role in regulating the intracellular trafficking and function of CTLA-4 protein. Three transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 1173 |
Clone Number: | ARC0522 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |