AP2M1 Rabbit Polyclonal Antibody (CAB2492)
- SKU:
- CAB2492
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | AP2M1 Rabbit Polyclonal Antibody |
SKU: | CAB2492 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 134-433 of human AP2M1 (NP_001020376.1). |
Sequence: | TQQG IKSQ TKEE QSQI TSQV TGQI GWRR EGIK YRRN ELFL DVLE SVNL LMSP QGQV LSAH VSGR VVMK SYLS GMPE CKFG MNDK IVIE KQGK GTAD ETSK SGKQ SIAI DDCT FHQC VRLS KFDS ERSI SFIP PDGE FELM RYRT TKDI ILPF RVIP LVRE VGRT KLEV KVVI KSNF KPSL LAQK IEVR IPTP LNTS GVQV ICMK GKAK YKAS ENAI VWKI KRMA GMKE SQIS AEIE LLPT NDKK KWAR PPIS MNFE VPFA PSGL KVRY LKVF EPKL NYSD HDVI KWVR YIGR SGIY ETRC |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | mu2; AP50; MRD60; CLAPM1; AP2M1 |
Positive Sample: | HeLa,293T,MCF7,A-549,U-87MG |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cytoplasmic side, Membrane, Peripheral membrane protein, coated pit. |
Calculated MW: | 50kDa |
Observed MW: | 50kDa |
This gene encodes a subunit of the heterotetrameric coat assembly protein complex 2 (AP2), which belongs to the adaptor complexes medium subunits family. The encoded protein is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes. The encoded protein may also play an important role in regulating the intracellular trafficking and function of CTLA-4 protein. Three transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 1173 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |