AP2M1 Rabbit Polyclonal Antibody (CAB13962)
- SKU:
- CAB13962
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | AP2M1 Rabbit Polyclonal Antibody |
SKU: | CAB13962 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 134-433 of human AP2M1 (NP_004059.2). |
Sequence: | TQQG IKSQ HQTK EEQS QITS QVTG QIGW RREG IKYR RNEL FLDV LESV NLLM SPQG QVLS AHVS GRVV MKSY LSGM PECK FGMN DKIV IEKQ GKGT ADET SKSG KQSI AIDD CTFH QCVR LSKF DSER SISF IPPD GEFE LMRY RTTK DIIL PFRV IPLV REVG RTKL EVKV VIKS NFKP SLLA QKIE VRIP TPLN TSGV QVIC MKGK AKYK ASEN AIVW KIKR MAGM KESQ ISAE IELL PTND KKKW ARPP ISMN FEVP FAPS GLKV RYLK VFEP KLNY SDHD VIKW VRYI GRSG IYET |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:100 - 1:500 |
Synonyms: | mu2; AP50; MRD60; CLAPM1; AP2M1 |
Positive Sample: | HeLa,Mouse brain,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cytoplasmic side, Membrane, Peripheral membrane protein, coated pit. |
Calculated MW: | 50kDa |
Observed MW: | 50kDa |
This gene encodes a subunit of the heterotetrameric coat assembly protein complex 2 (AP2), which belongs to the adaptor complexes medium subunits family. The encoded protein is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes. The encoded protein may also play an important role in regulating the intracellular trafficking and function of CTLA-4 protein. Three transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 1173 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |