AP2B1 Monoclonal Antibody (CAB23784)
- SKU:
- CAB23784
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
AP2B1 Monoclonal Antibody (CAB23784)
The AP2B1 Monoclonal Antibody is a highly specific antibody designed for research involving AP2B1, a critical component of the adaptor protein complex 2 (AP-2). This antibody, produced through hybridoma technology, is ideal for studying the role of AP2B1 in clathrin-mediated endocytosis, a fundamental process for the internalization of cell surface receptors and other molecules.AP2B1 is essential for the formation of clathrin-coated vesicles, which play a crucial role in various cellular processes such as receptor trafficking, nutrient uptake, and signal transduction. The AP2B1 Monoclonal Antibody is validated for use in immunofluorescence, immunoprecipitation, and other biochemical assays, enabling researchers to explore the function of AP2B1 in different cell types and experimental settings.
By targeting AP2B1 with this monoclonal antibody, researchers can gain insights into the mechanisms underlying clathrin-mediated endocytosis and its implications for cellular physiology and disease processes. Studies using the AP2B1 Monoclonal Antibody can contribute to the development of novel therapeutic strategies targeting endocytic pathways in conditions such as cancer, neurodegenerative disorders, and infectious diseases.
| Product Name: | AP2B1 Monoclonal Antibody |
| Product Code: | CAB23784 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC61904 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | Hela, Mouse lung, Rat testis |
| Cellular Location: | Cell membrane, Cytoplasmic side, Membrane, Peripheral membrane protein, coated pit |
The protein encoded by this gene is one of two large chain components of the assembly protein complex 2, which serves to link clathrin to receptors in coated vesicles. The encoded protein is found on the cytoplasmic face of coated vesicles in the plasma membrane. Two transcript variants encoding different isoforms have been found for this gene.
| Immunogen: | Recombinant protein of human AP2B1. |
| Sequence: | Email for sequence |
| Synonyms: | AP2B1, ADTB2, AP105B, AP2-BETA, CLAPB1, AP-2 complex subunit beta |
| Calculated MW: | 98kDa/104kDa/105kDa |
| Observed MW: | 105kDa |
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